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A new weight-loss drug which has anti-addiction drug naltrexone has become approved by the U.S. Food and Drug Administration today, the business said in a very statement.

Using two separate drugs to lose weight can be very effective there are combinations while watching FDA now awaiting approval. When dealing with fat loss and the people that go through it you should err on the side of caution and allow the FDA do its job and demand some investigation be done so that the public is aware of the side effects and dangers of the medications before we bring them. Keep in mind that drug companies will be in business to generate money and that they would say almost anything to keep people on his or her medications.

Researchers found that participants investing in this drug for a year, dropped a few pounds within one month and have kept the weight off throughout the 56 weeks with the study. Contrave is really a combination of the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs which can be made up of several active ingredient, which might make them more effective and safer.

Combo-pilling will be the newest fad or also the newest to come under scrutiny and for that reason it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular may be the fact that as of right now there aren't any long term prescription weight loss supplements that have been authorized by the FDA aside from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications and some of the combinations are actually rejected or have yet to be approved by the FDA.

Seizures are a side effect with Contrave and really should not be taken in people with seizure disorders. The drug may also raise blood pressure level and heart rate, and really should not be used in people with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with all the drug.

The FDA also warned that Contrave can raise blood pressure levels and heartbeat and must not used in patients with uncontrolled high hypertension, along with by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients using a history of cardiac arrest or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes using a boxed warning to alert medical professionals and patients for the increased chance of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stopping smoking.


Approving a drug with this many potentially lethal unwanted side effects is inconsistent with the mission statement in the FDA. The power of the drug manufacturing lobby is blatantly evident in the approval of many drugs requiring 'post-marketing' studies which are clearly significant to overall drug safety within the US.